The DeCapper optimizes the workflow in a laboratory by decapping 12 rows of tubes simultaneously in less than 60 seconds. The DeCapper supports 0.3 mL to 1.4 mL micro tubes from Matrix, Micronic and Nunc. It can be controlled by VENUS software or a stand-alone controller. Caps can be placed on a separate cap holder for processing multiple plates. In addition, this system can be operated as an integrated and stand-alone unit simultaneously.